Anti-mycobacterial activity of Withania somnifera and Pueraria tuberosa against Mycobacterium tuberculosis H37Rv

Mycobacterium tuberculosis is a leading cause of morbidity and mortality worldwide. Mycobacterium tuberculosis infects about one third of world population and tuberculosis remains the most frequent cause of death due to a single infectious disease. Anciently, herbal plants have established home remedies for many of common alignments, diagnostic procedures and preventive measures. Using this strategy, this study was proposed to find out anti-tuberculosis activity of medicinal plants viz. Withania somnifera and Pueraria tuberosa against M. tuberculosis H37Rv. Mycobacterium tuberculosis activity was tested using minimal inhibitory concentration method (MIC). Aqueous extract of W. somnifera (0.01-1.0 mg/mL) had significant effect against M. tuberculosis whereas, P. tuberosa in higher concentration showed no inhibition. The outcomes are possibly demonstrating a comprehendible evidence of the effective anti-tubercle activity of W. somnifera.